Weight Loss and Endothelial Function in Obesity
نویسندگان
چکیده
منابع مشابه
Weight loss and endothelial function in obesity.
Endothelial dysfunction, a pathologic feature of obesity, predicts the occurrence of cardiovascular disease (1,2), and is felt to mediate the increased cardiovascular risk associated with a number of classical and nonclassical risk factors. However, the pathogenesis of endothelial dysfunction in obesity remains uncertain. In this field, the major questions center on the relative roles of insuli...
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OBJECTIVE Obesity is associated with a high risk for atherosclerotic cardiovascular disease. There is a causal association between obesity, inflammation, insulin resistance (IR) and endothelial dysfunction. The aim of this study was to evaluate changes in IR, proinflammatory state and markers of endothelial dysfunction in morbidly obese patients after weight loss following bariatric surgery. ...
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In nondiabetic subjects, obesity is associated with a modest expansion of beta-cell mass, possibly amounting-according to the best available estimates-to 10-30% for each 10 kg of weight excess. Whether age of onset and duration of obesity, recent changes in body weight, and body fat distribution have any effect on beta-cell mass in humans is unknown. Both fasting insulin secretion and the total...
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Lessons Learned from a Community Based Lifestyle Intervention for Youth at Risk for Type 2 Diabetes Eva M Vivian1*, Lisa H Colbert2, Patrick L Remington3 1University of Wisconsin-Madison, School of Pharmacy, Madison, USA 2Departments of Kinesiology and Population Health Sciences, 2035 Gymnasium-Natatorium, 2000 Observatory Drive, Madison, USA 3UW School of Medicine and Public Health, Health Sci...
متن کاملObesity & Weight Loss Therapy
Type 2 Diabetes Mellitus (T2DM) is the most common and costly endocrine disease [1] which is associated with increased morbidity and premature death, especially from cardiovascular diseases, myocardial infarction and stroke [2]. The prevalence of T2DM has increased dramatically over the past two decades. According to the most recent survey, the number of people who are currently affected by thi...
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ژورنال
عنوان ژورنال: Diabetes Care
سال: 2003
ISSN: 0149-5992,1935-5548
DOI: 10.2337/diacare.26.6.1927